Manchester City on Saturday thrashed 10-man Liverpool 5-0 after Sadio Mane was shown a red card.
Aguero had earlier put Manchester City in front with a goal, before Mane was sent off eight minutes before half-time for a high challenge on Ederson.
Ederson was later replaced by Claudio Bravo.
Gabriel Jesus’ header added a second goal for City, taking advantage of Liverpool’s numbers.
Aguero set up Jesus for his second after the break before substitute Leroy Sane added two late goals to give City their biggest win over Liverpool since 1937.